Multi-Instance Whole Genome Sequencing GATK4.0 Workflow

We’ve published the Multi-Instance Whole Genome Sequencing BWA/GATK 4.0 workflow. This workflow keeps a similar price, with the improvement in total execution time of up to 3.0 times compared to a single-instance implementation. The Multi-Instance Whole Genome Sequencing workflow processes a 30x whole genome in as little time as 3 hours without any additional computational resource such as GPU or FPGA. The differences in precision, recall and f-score between multi-instance and single-instance workflows are lower than 0.001%, which is expected due to stochastic effects.

See the workflow on the Seven Bridges Platform.

Marko Marinkovic